Prevalence of Thyroid Disorders in First Trimester of Pregnancy at Kathmandu Model Hospital

Abstract

Introduction: Thyroid disorder is a common endocrine disorder in pregnancy. The reference range of thyroid function is lower in pregnancy. Optimum thyroid function is required to prevent complications in mother and fetus. Pregnant ladies without symptoms of thyroid disorder may have abnormal value. This study was done to find the prevalence of thyroid disorder in pregnant ladies attending Kathmandu Model Hospital in first trimester.
Methods: This was an observational study of pregnant ladies who attended Obstetrics and Gynecology Department of Kathmandu Model Hospital from September 2021 to February 2022.  Pregnant ladies in first trimester with singleton pregnancy without history of thyroid disorder were included in the study. Thyroid function test (TFT) was done after obtaining consent. Data were collected and analyzed.
Results: A total of 488 pregnant ladies were included in the study. Thirty-seven (7.58%) pregnant ladies had abnormal result, out of which 34 (6.96%) had subclinical hypothyroidism (SCH).
Conclusion: Subclinical hypothyroidism was high in the present study and BMI was not associated as risk factor.