Granulomatous Inflammation of Gall Bladder

Abstract

Granulomatous cholecystitis is a condition affecting the gallbladder that is often confused with cancers and other types of cholecystitis, which poses a diagnostic challenge for medical professionals. We share a case of granulomatous cholecystitis in a 51-year-old man with resolving acute pancreatitis and hypertension. Imaging showed thickening of the gallbladder wall and presence of gallstones. Laparoscopic cholecystectomy was performed and histopathological examination confirmed that the patient had granulomatous cholecystitis, characterized by presence of epithelioid histiocytes and multinucleated giant cells. The case highlights the importance of considering granulomatous cholecystitis in the differential diagnosis of gallbladder diseases, especially in patients presenting with chronic inflammation and gallstones. This report underscores the need for high clinical suspicion to differentiate granulomatous cholecystitis from other gallbladder pathologies.